I've joined because of a specific project: helping an elderly friend on the verge of dementia to continue using TV actively rather than passively! The specific problem is an inability to understand the succession of channels going "up" or "down" - so a standard big-button remote with on/off, volume up/down, and channel up/down wouldn't help.
(Here in the UK it's BBC1, BBC2, ITV, Channel 4, Channel 5, ITV2...)
An added complication is it's not just a TV - there is a set-top box (PVR) involved providing an easier-to-read interface than the TV itself. I am loath to take the PVR out of the equation because suddenly things would become unfamiliar, but sometimes the TV reverts to tuner instead of HDMI (especially if she presses the wrong button in the existing universal remote - a Harmony 300). So a "solution" will require macros.
I bought a One For All URC1280 with the intention of experimenting with JP1, and with the prospect of using its innards connected to a custom made keypad with big buttons labelled "BBC1", "BBC2" etc... and especially a button marked "FIX" which makes sure the PVR is on and the TV is on HDMI. For nice buttons I have cannibalised a cheap wireless keyboard - which has provided a quantity of buttons with scissor mechanisms, and a redundant Sky box has provided 16 push switches (and a USB WI-FI module!).
The URC1280:

My next step is to explore the facilities of JP1, hence researches lead here. I have downloaded the software and it runs on my Linux system.
As my PC has a motherboard with serial port, I figure I can hook up the JO1 to that rather than obtain a USB to Serial adapter. Gleaning from here: http://www.hifi-remote.com/wiki/index.php/JP1_Cables, the JP1 pin allocations are
1 - VDD
2 - RTS
3 - GND
4 - TXD
5 - NC
6 - RXD
A serial port doesn't have VDD, so is it OK to hook that up to +5V?
Unfortunately the connector on the URC1280 doesn't look the same as illustrated elsewhere. I can see pin 1 identified, but nothing to say whether it is JP1.4 or what. The access hole is differently shaped:

I'll blog progress, which I hope will be useful to somebody.
Am I on the right track so far? Tips please people.